This is Possible for all Office types but sadly not possible for PDF documents . Supported Types: - Microsoft Office InfoPath forms - The 97-2003 file formats for the following Microsoft Office programs: Word, Excel, and PowerPoint - The Office Open XML Formats for the following Microsoft Office programs: Word, Excel, and PowerPoint - The XML Paper Specification (XPS) format If its for Office type Documents then, You can do this by enabling Information Rights Management IRM. >You can use Information Rights Management (IRM) to help control and protect files that are downloaded from lists or libraries. > >Microsoft Active Directory Rights Management Services (AD RMS) supports Information Rights Management for sites. No separate or additional installations are required. > >To apply IRM to a list or library, you must have administrator permissions for that list or library. > >Before you apply IRM to a list or library it must first be enabled by an administrator for your site. More details steps available at https://support.office.com/en-us/article/Apply-Information-Rights-Management-to-a-list-or-library-3bdb5c4e-94fc-4741-b02f-4e7cc3c54aa1?ui=en-US&rs=en-US&ad=US https://support.office.com/en-us/article/Restrict-permission-to-content-in-a-file-3cdd7eda-79d4-471f-91af-4dd02cc6f764