I am trying to create a new site collection in my sandbox environment via central administration and receive the below error: >UserProfileApplicationNotAvailableException_Logging :: UserProfileApplicationProxy.GetRawPartitionID has null proxy I am having the same issue as this open post via Office Dev center and have tried all suggestions in the post. https://social.msdn.microsoft.com/Forums/office/en-US/49d55dc2-60f9-4434-b140-d9b2d68372d8/sharepoint-2013-cannot-create-site-collection?forum=sharepointadmin I have also tried creating the site collection via PowerShell. Ran Config Wizard post patch, IIS reset, server reboot, starting the User Profile service etc. Like the above post, we have implemented the 10/17 patch and do not need UPA in this environment as it is solely a test box.