I found this technet post moving the database: http://social.technet.microsoft.com/Forums/en-US/40701cb5-05a8-4a8a-9cf2-8be0e632a2f5/moving-sharepoint-database-from-one-drive-to-other?forum=sharepointadminlegacy
As part of the steps it says to stop various sharepoint services, which I have almost completed. The last service it says to stop is the World Wide Web Publishing Service which I have not stopped yet.
My concern is that TFS (version 2010, I know, I know but I didn't set it up) is also running from the same box using the same IIS and I don't want employees to be interrupted, tfs wise (other than sharepoint and SSRS).
My question is will there be any issues with sharepoint (or tfs for that matter) if we DON'T stop the world wide and continue on with the steps in the post?
I ended up just needing to stop the sharepoint related sites in IIS instead of shutting down the entire WWW service.