What will happen if a user's profile is set to be disabled and moved(from Users OU) to the Disabled Users OU(just another OU)? does SharePoint deletes the user profile and properties?
As long as you set the User Profile Sync to omit the Disabled User OU, the users will be removed from the import. You can also add the additional check for "disabled" but simply changing OU will work.
Also, ensure that you are regularly running a search crawl of the User Profiles so that the user is removed from Search Results.
It depends on how your user profile service application is setup.
Check settings here to determine whether user profiles will be removed:
User Profile Service Application > Configure Synchronization Connections > Edit Connection Filters > Exclusion Filter for Users
As for whether my sites will be removed for users removed from the user profile store, it depends on whether the My Site Cleanup Timer Job is running in your farm. You can disable the job if you would like to manually manage my site cleanup.
For more info on the My Site Cleanup Timer Job (2010) see this great post from Kirk Evans.
The My Site Cleanup Job is responsible for deleting user profiles and My Sites of those users. This includes the following activities:
- Remove user profiles that are queued for deletion.
- If those users have a My Site, assign the user’s manager as the SPSite.SecondaryContact. Email the manager letting them know that the user’s My Site will be deleted in 14 days.
- 11 days after the first notification, email the manager again letting them know that the My Site will be deleted in 3 days.
- After a total of 14 days, delete the MySite.