From one of our users:
Now that many of the items seem to work with Sharepoint and Chrome, one of the biggest outstanding issues is that it wants to open the documents in the browser by default.
Opening in the browser does not support simple/common EXCEL functions and results in errors being thrown and me getting hate emails
When using Google Chrome I would like to click on an Excel spreadsheet and have it open with my local application verses asking to save it to a file.