I am unable open my list in data sheet list view mode in Chrome browser but I am able to open in IE.
Does any one know what kind of settings I need to change.
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IE makes use of a Web Datasheet Component (I believe via an ActiveX control), but Chrome uses "extensions" which are not supported at the moment. Refer to this article: http://veroniquepalmer.wordpress.com/2012/02/06/sharepoint-2010-compatibility-with-google-chrome/