I am trying to open a .pptx document in my sharepoint 2013 site collection and i am getting this error
domainnameowa.com refused to connect.
What would be the workarounds?
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It looks like you have an Office Web Apps or Office Online Server bound to the farm but that server isn't accepting connections for one reason or another.
Since you haven't provided enough info to troubleshoot the issue, you'll need to talk to your administrators of OWA/OOS/SharePoint to track down the issue.
So After trying so much i found an easy way to this issue
Just raise a request to respective team in your organization to turn off protective mode of the site.
To check open the site and see the Properties then you will see like shown below in "ZONE"
Trusted Sites are different than protected mode. Protected Mode affects how IE will process certain items for security reasons.
Trusted Sites lets a site do pretty much anything it wants. It sounds like a good idea, but a hacker with any significant skills could really own your system if they attacked a site that happened to be in your trusted sites list.