yes it is possible and it is really easy.
In SPO Library click on Flow and click Create a flow:
Click See more and select When a new file is added in SharePoint, complete a custom action: (trigger will be automatically set) or you can create flow with different trigger (next picture) (timer - like once per day/ when file eidted,....)
After this in flow you can work with file properties - depends if you have already loeaded file properties with trigger or loading all with Get- List Items function ald load items from list (can be based on some filter)
After this create Condition function where you will set the condition and in the states you can use Office 365 - Send Email function
*If yo are working with more than one file/item there will be "Apply to each" loop*, otherwise you will work only with the Condition.
In the condition set, what you want. After this Send Email, there are two versions of functions, take which is more suitable to you.
The whole flow will looks like this:
This is very easy manual created in few minutes. If you need more information or make some easy Flow just contact me and we can do something via TeamViewer.
Hope it helps!