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I want to use drop down control on SharePoint framework webpart(done) and on change event to call some method/ some rest api and so.but it is not allowing.

I did not find any article where spfx web part is shown with drop down. whereever I found drop down, it was in web part edit mode.I am sure end user will laugh if I go and say hay edit web part, and choose drop down to change the data.

some body have achieved ?

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Hope my test demo here which use AsyncDropdown of gitHub would helpful for you.

Here is the thread for your reference.

https://social.technet.microsoft.com/Forums/office/en-US/f7ef7840-43c9-4158-a29c-c654c1de753c/cascading-dropdown-using-office-ui-fabricreact-dropdow?forum=SP2016

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