3

I wanted to give another department head access to be able to update the user profile service (specifically update Manager Field)? Is this possible or any other way to do it?

2

Due to limitations of SPO, only SharePoint Admin role can manage the UPA service. On-prem we have the option where we can add any user as administrator of the Service application.

check this Add and edit user profile properties

4

No. The user(s) must have the SharePoint Administrator role.

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