Yes it seems to be possible, for that you need to enable Item level permission and give separate permission to each of your folders.
Below are steps from Ref link
Break permission inheritance on a folder, document, or list item
By default, folders, documents, and list items inherit permissions from their parent securable object. In most cases, this means that they inherit their permissions from the list or library that contains them. In the case where folders, documents, and list items are contained by other folders, they would, by default, inherit permissions from the folder that contains them. Use the following steps if you want to break this inheritance and create unique permissions on a particular folder, document, or list item.
At a later time, you can choose to re-inherit permissions from the parent securable object. Note that inheriting permissions from the parent discards any unique permissions that may have been created for this securable object, such as unique SharePoint groups or permission level assignments that were created at this securable object while using unique permissions.
Open the list or library that contains the folder, document, or list item on which you want to break inheritance from the parent securable object.
Rest the pointer on the folder, document, or list item on which you want to break inheritance, click the arrow that appears, and then click Manage Permissions.
The Permissions page displays all users and SharePoint groups on this securable object and their assigned permission levels.
The page description describes the inheritance status for this securable object. Also, check boxes appear next to the Users/Groups column if unique permissions are being used for this securable object. If check boxes do not appear next to the user and group names on the Permissions page, permissions are being inherited from a parent securable object.
On the Actions menu, click Edit Permissions, and then click OK to confirm the action.
NOTE: The Edit Permissions option is not available on the Actions menu if this securable object has unique permissions that are not being inherited from the parent securable object.