Is this at all possible?
I've been told to do it and do not know how.
I'm using Sharepoint 2010

  • Are you sure you are asking if using Permission in a SharePoint site the USB port access on a server/workstation can be blocked? If that is your question then Dennis has answered your query. – Manu Jan 21 '15 at 13:19

This is not possible. Share point is not something that controls the PC environment.

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