I've got a Sharepoint Online subsite that has libraries that function basically entirely on unique permissions because its heavily used by external users the permission structure is not exactly standard.
The issue we keep running into is that someone will go to remove a user permission and accidentally click on Delete Unique Permissions. This deletes all of the unique permissions. So if they managed to click on it at the subsite level we lose all of the library permission settings. Through my conversations with Microsoft there isn't an easy way to recover permission settings. It would be nice to remove the ability to click that button for this particular subsite.