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Do you have to use permissions to route your content to target your users? If not you can maybe use content by search webpart with query parameters to filter articles on users country in their profile? We have just done the same for an intranet for 18,000 users, targeting content based on location and organization.
Have you thought about using Folders? That 50k limit is just a recommendation because performance starts to plummet after that point, but the limit refers specifically to unique permissions per container. Therefore you could divvy up the items into folders, and your solution will still remain performant. You would simply just apply the permissions to the ...
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