After installing the hotfix:
My Synchronization connection to the AD cannot be populated, because I get a "Method not found" exception:
Method not found: 'Int32 Microsoft.Office.Server.Administration.UserProfileApplicationProxy.get_LdapConnectionTimeout()'.
It looks like an inconsitency, between different parts of the SharePoint installation, where the proxy class does not contain the requested property. To confirm this claim, I ran from powershell:
// after mounting the SPServiceApplicationProxy class in a variable $proxy.... $proxy | Get-Member
It returns a reflection of the object - a list of properties and methods, and yes... there is no LdapConnectionTimeout.