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I've got a feeling I'm in for a world of pain here but all of a sudden (I can't think of what might have caused it) my central admin is giving me a 503 error and when I attempt to access my site I'm getting an:

"System.NullReferenceException: Object reference not set to an instance of an object. at Microsoft.Office.Server.Administration.UserProfileApplicationProxy.get_ApplicationProperties() "

Is there someway I can do some sort of reset (or at least some checks to attempt to diagnose the issue) here through powershell or something?

ANY help at all greatly appreciated.

UPDATE: I can get to _layouts/settings.aspx. So I'm making the assumption is with my home.aspx - but I'm running in debug mode and not getting an error in VS so I'm assuming it's configuration?

I have checked through IISManager that only anonymous and windows authentication are enabled for my SharePoint Web Services site.

EDIT

===========================================

Ridiculous of me to omit this detail - yesterday my windows password expired; so obviously, this is affecting the authentication. What's the best way to deal with a password expiry having this sort of impact?

I've ran:

"stsadm -o updatefarmcredentials -userlogin "domain\my_user" -password "password""

And noticed my sharepoint central admin service was stopped in the application pools section of IIS - so started it. Now it's a 500 error. Having no luck here.

That previous command has now granted me access to the main site. I can now continue development fortunately - still no luck with central admin though and it's only a matter of time before I'll need to access it.

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