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How do I control the type of document (only .docx allowed) is being uploaded in one of the SharePoint 2010 document libraries?

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Already answered… – Hugh Wood Aug 28 '12 at 10:37

Through central administration you can block upload file types.

central admin -> Operations -> Blocked FileTypes -> now select the site and add the extension you want to block.

you can read on this:

or as hugh stated have an eventReciver to handle it for selected document libraryies only

Preventing document Uploading to Document Library in SharePoint 2010

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