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When I select the connection for the default managed metadata service application (Managed Metadata Service) and click properties it generates: The remote server returned an error: (403) Forbidden. I checked ULS logs I found: Exception returned from back end service. System.ServiceModel.Security.MessageSecurityException: The HTTP request was forbidden with client authentication scheme 'Anonymous'. ---> System.Net.WebException: The remote server returned an error: (403) Forbidden.

(the current user is Administrator and has been added to managed metadata service application permissions. Thanks for your advices.

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Is the Managed Metadata running on the same server as the Web Front end? If not are you running Kerberos? –  Per Jakobsen May 21 '12 at 19:07
Yes, Managed Metadata running on Web front end. and I am running Kerberos. –  Medes May 22 '12 at 7:43

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